Bitter-Bloc™ WS/OS Liquid Concentrate

Bitter-Bloc™ WS/OS Liquid Concentrate is SpecializedRx's original proprietary anhydrous water soluble/oil soluble liquid concentrate Bitter-Bloc™ formula.

Appearance: 

Tan opaque liquid

Typical Applications:

• Pediatric medications
• Geriatric medications
• Veterinary medications
• Vitamin supplements
• Bitter APIs

Highlights:

• Anhydrous
• Water soluble
• Non-GMO
• GRAS status
• Heat stable
• No allergy declarations
• Low pH stable
• Preservative and dye-free
• Low starting use level

Bitter-Bloc™ WS/OS Liquid Concentrate Use:

• Concentration Level: 37500 ppm
• Starting Use Level: 100 ppm - 600 ppm
• Mean Drop Volume: 40 µl (25 drops = 1 mL)
• In a 30 mL preparation, 0.08 mL (2 drops) = 100 ppm, 0.4 mL = 500 ppm  

• In a 150 mL preparation, 0.4 mL (10 drops) = 100 ppm; 2 mL = 500 ppm

How Bitter-Bloc™ Technology Works:

Bitter-Bloc™ is an advanced protein technology that naturally blocks flavor defects in various applications, addressing palatability issues found in many APIs and excipients. Unlike other products that merely mask unpleasant flavors, this innovative solution effectively prevents these defects from reaching taste buds, resulting in a cleaner taste profile. This organic, water soluble protein has been validated by third-party studies to modulate over 16 of the 25 bitter taste receptors on the tongue, significantly reducing bitterness perception. Additionally, it eliminates salty, metallic, astringent, and other off-notes in liquid, powder, or tablet-based oral formulations. With its versatile formulation capabilities, this protein technology offers a comprehensive solution for improving the taste profiles of compounded prescriptions, enhancing patient compliance and satisfaction.

Q: How much Bitter-Bloc™ do I need?
A: Typically, the more bitter something is, the more Bitter-Bloc™ is needed. Typically, most aqueous formulas are effective around 100-500 ppm.

Q: Is Bitter-Bloc™ a sweetness modulator?
A: Bitter-Bloc™ is not a sweetness modulator as it does not affect
sweetness. However, in some cases tasters will notice an enhanced flavor profile. Since bitterness is a strong flavor, it often will overpower the other flavors present. Bitter-Bloc™ will bring down the bitterness perception to the point that other flavors are able to be better perceived.

Q: Are there any applications where Bitter-Bloc™ will not work?
A: Although Bitter-Bloc™ is effective in most applications, it will not work with an active organism present such as an active probiotic. 

Additional Information:

MSDS: Available upon request

Technical Data Sheet: See resources

Taste Receptor Activity and Stevia Case Studies: PDF

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